Paul Sorajja
Dr. Paul Sorajja is an interventional cardiologist at Banner Health in Phoenix, AZ. He received his M.D. from Mayo Medical School and completed his Internal Medicine Residency and Cardiology Fellowship at the Mayo Graduate School of Medicine. Dr. Sorajja joined the Mayo Clinic staff in 2006, achieving the rank of Professor of Medicine in 2012. In 2013, Dr. Sorajja joined the Minneapolis Heart Institute. In 2025, Dr Sorajja joined Banner Health.
Dr. Sorajja's clinical practice specializes in interventional cardiology, with a focus on catheter-based therapy of valvular and structural heart disease. He was part of the team that performed the first transcatheter mitral valve replacement in the U.S. for native mitral regurgitation in 2015 and has one of the highest worldwide experiences with TMVR. Dr. Sorajja has served or serves as the global or national PI for many early feasibility and pivotal clinical trials in valve disease, with the most recent notable contribution being the TRILUMINATE pivotal trial that was published in the New England Journal of Medicine as the first randomized trial for tricuspid therapy. He is known especially for performing many first-in-human therapies in valve disease including the first TriClip (2017), MitraClip laceration and TMVR (2018), dedicated TMVR in severe MAC (2016), vDyne (2021), MitraClip for HCM (2016), among many others. Dr. Sorajja has published over 500 manuscripts and book chapters, with expertise in cardiac hemodynamics, clinical education, hypertrophic cardiomyopathy, and percutaneous therapy of structural heart disease. He has served in leadership positions in multiple national societies and is a founding Board member of the Cardiovascular Innovations Foundation.
Dr. Sorajja has been an editor-in-chief for numerous textbooks on cardiac catheterization, including his Structural Heart Disease atlas. He has served as a program director for interventional cardiology fellowships, and has received awards in medical education. In 2017, he received the Robert G. Hauser Award for Leadership Excellence in Innovation from the Minneapolis Heart Institute Foundation. Dr. Sorajja is highly active in intellectual property development and start-up companies.